Interleukin 6 and 10 Serum Levels and Genetic Polymorphisms in Children with Down Syndrome

Table 2

IL-6 and IL-10 serum levels in relation to the genotypes.

Models	Genotype	DS (pg/ml)	value	Control (pg/ml)	value	Genotype	DS (pg/ml)	value	Control (pg/ml)	value
	IL-10 -1082A>G					IL-6 -597G>A
Codominant	AA	15.07	0.82	13.60	0.69	GG	11.52	0.49	16.22	0.12
	AG	15.02		14.33		GA	13.59		19.12
	GG	16.84		13.71		AA	12.17		11.00
Dominant	AA	15.07	0.91	13.60	0.59	GG	11.52	0.27	16.22	0.89
	AG/GG	16.08		14.30		GA/AA	13.32		12.80
Recessive	AA/AG	15.02	0.62	14.09	0.75	GG/GA	13.04	0.90	16.74	0.07
	GG	16.84		13.71		AA	12.17		11.00
	IL-10 -592C>A					IL-6 -174G>C
Codominant	CC	16.84	0.57	14.03	0.94	GG	11.52	0.49	16.22	0.12
	CA	15.18		14.08		GC	13.59		19.12
	AA	14.72		14.27		CC	12.17		11.00
Dominant	CC	16.84	0.47	14.03	0.94	GG	11.52	0.27	16.22	0.89
	CA/AA	15.02		14.08		GC/CC	13.32		12.80
Recessive	CC-CA	15.58	0.31	14.08	0.90	GG/GC	13.04	0.90	16.74	0.07
	AA	14.72		14.27		CC	12.17		11.00
	IL-10 -819C>T					IL-6 -572G>C
Codominant	CC	16.84	0.57	14.03	0.94	GG	13.77	0.07	13.67	0.99
	CT	15.18		14.08		GC	10.65		16.73
	TT	14.72		14.27		—	—		—
Dominant	CC	16.84	0.47	14.03	0.90	GG	—	—	—	—
	CT/TT	15.02		14.08		GC/−
Recessive	CC/CT	15.58	0.31	14.08	0.90	GG/GC	—	—	—	—
	TT	14.72		14.27		—

Genotype was not found. DS: Down syndrome.