Monocyte Chemoattractant Protein-1 in Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis: Biomarker Potential and Association with Polymorphisms in the MCP-1 and the CC Chemokine Receptor-2 Gene

Table 2

Correlation between uMCP-1 and other biomarkers (, ).

		S-CRP	S-LPK	S-creatinine	S-cystatin C	Urine albumin creatinine index	Anti-PR3-ANCA	Capture PR3-ANCA	Anti-MPO-ANCA	BVAS
uMCP-1	Correlation coefficient	0.28	0.101	0.104	−0.09	0.24	0.005	0.10	0.09	0.16
	value	0.0002	0.057	0.052	0.526	0.0003	0.952	0.204	0.477	0.0002
	N	348	352	351	54	247	134	180	64	629
uMCP-1/urine creatinine index	Correlation coefficient	0.29	0.16	0.19	−0.17	0.33	−0.03	0.14	0.14	0.15
	value	0.0003	0.003	0.0004	0.224	0.0006	0.746	0.06	0.256	0.0002
	N	346	350	349	54	246	134	180	64	627

uMCP-1: urinary monocyte chemoattractant protein; S-CRP: serum C-reactive protein; LPK: white blood cell count; PR3: proteinase 3; ANCA: antineutrophil cytoplasmic autoantibodies; MPO: myeloperoxidase; BVAS: Birmingham vasculitis activity score.