Levistilide A Ameliorates NLRP3 Expression Involving the Syk-p38/JNK Pathway and Peripheral Obliterans in Rats

<div>LA anti-inflammatory mechanism diagram. LA inhibited the activity of p38/JNK by decreasing Syk phosphorylation, thereby inhibiting the downstream NLRP3 inflammasome gene expression and the secretion of its related proteins (IL-1<i>β</i> and IL-18).</div>

Mediators of Inflammation

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Figure 6

Figure 6: Levistilide A Ameliorates NLRP3 Expression Involving the Syk-p38/JNK Pathway and Peripheral Obliterans in Rats 