Research Article

A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer’s Disease

Table 1

Characteristics of the studied groups.

ParameterAD subjects ()Controls ()

Gender ratio: male/female31/7378/1280.16
Mean (years)79.46 ± 6.1676.22 ± 6.85<0.0001
Mean onset (years)77.4 ± 6.47
MoCA score13.62 ± 5.7228.52 ± 1.36<0.0001
ApoE-ε4 positivity (yes/no)39/6541/1650.0008

SD: standard deviation; MoCA: Montreal Cognitive Assessment; is considered as significant.