Table 1: Comparison of perioperative findings between patients with and without acute kidney injury after living donor liver transplantation.

nNon-AKI groupAKI groupp
17353

Preoperative recipient factor
Age (years)53 (48–59)53 (49–60)0.728
Gender (male)115 (66.5%)44 (83.0%)0.021
Body mass index (kg/m2)24.1 (21.8–25.9)24.4 (22.2–28.1)0.222
Etiology0.173
Alcohol32 (18.5%)12 (22.6%)
Hepatitis B102 (59.0%)36 (67.9%)
Hepatitis C11 (6.4%)1 (1.9%)
Autoimmune5 (2.9%)0 (0.0%)
Drug & toxin11 (6.4%)4 (7.5%)
Cryptogenic findings12 (6.9%)0 (0.0%)
MELD score (points)14 (9–22)15 (10–25)0.275
Complications of hepatic decompression
Severe encephalopathy12 (6.9%)2 (3.8%)0.528
Varix44 (25.4%)13 (24.5%)0.878
Ascites (≥1 L)67 (38.7%)26 (49.1%)0.181
Laboratory value
Hematocrit (%)30.1 (25.2–36.3)28.4 (25.3–32.2)0.146
Sodium (mEq/L)139.0 (135.0–142.0)139.0 (136.0–141.0)0.763
Creatinine (mg/dL)0.8 (0.7–1.0)0.7 (0.6–0.9)0.015
MDRD GFR (mL/min/1.73 m2)96 (72–128)117 (86–158)0.015
C-reactive protein (mg/dL)0.3 (0.1–0.9)0.7 (0.2–1.7)0.004
Platelet (×109/L)67.0 (47.0–119.5)52.0 (38.5–77.0)0.006
Total bilirubin (mg/dL)2.0 (0.8–6.7)2.5 (1.1–8.3)0.354
International normalized ratio1.4 (1.2–1.8)1.6 (1.3–1.9)0.093
Intraoperative recipient factor
Total operation duration (min)525 (455–574)495 (465–560)0.522
Severe postreperfusion syndrome28 (16.2%)19 (35.8%)0.002
Blood product transfusion (unit)
Packed red blood cell6 (3–11)8 (5–12)0.057
Fresh frozen plasma6 (4–10)8 (5–13)0.006
Platelet concentrate0 (0–6)5 (0–10)0.035
Cryoprecipitate0 (0–0)0 (0–0)0.090
Hourly fluid administration (mL/kg/h)10.1 (7.9–12.6)8.2 (6.4–13.1)0.174
Hourly urine output (mL/kg/h)1.4 (0.8–2.2)1.1 (0.7–1.9)0.085
Furosemide administration (mg)5 (0–20)10 (0–33)0.094
Donor-graft factor
Age (years)31 (24–41)36 (28–48)0.027
Gender (male)76 (43.9%)21 (39.6%)0.524
Body mass index (kg/m2)23.0 (21.1–25.4)23.0 (21.4–25.9)0.587
Graft volume to standard liver volume ratio at time of transplantation (%)55.4 (48.5–65.4)53.5 (47.3–64.4)0.505
Steatosis percentage (%)3.0 (0.0–5.0)4.0 (0.0–5.0)0.958
Total ischemic time (min)98 (71–124)102 (70–158)0.366

AKI: acute kidney injury; MELD: model for end-stage liver disease; MDRD: the Modification of Diet in Renal Disease Study equation; GFR: glomerular filtration rate. Severe encephalopathy: West-Haven criteria III or IV. Values are expressed as numbers (portions) and median (interquartile).