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Mediators of Inflammation
Volume 2018, Article ID 8430614, 10 pages
https://doi.org/10.1155/2018/8430614
Research Article

Dietary n-3 PUFA May Attenuate Experimental Colitis

1INSERM UMR 1073, UFR de Médecine-Pharmacie, 22 boulevard Gambetta, 76183 Rouen Cedex, France
2Department of Gastroenterology, Rouen University Hospital, 1 rue de Germont, 76031 Rouen Cedex, France
3University of Calgary, Gastrointestinal Research Group, Snyder Institute for Chronic Diseases, Calgary, AB, Canada
4Center for Advanced IBD Research and Treatment, Kitasato Institute Hospital, Tokyo, Japan
5Nutrition Unit, Rouen University Hospital, 1 rue de Germont, 76031 Rouen Cedex, France
6Institute of Translational Medicine, University of Birmingham, Birmingham, UK

Correspondence should be addressed to Subrata Ghosh; moc.liamy@hsohgus

Received 28 July 2017; Revised 13 October 2017; Accepted 31 October 2017; Published 15 February 2018

Academic Editor: Sung-Ling Yeh

Copyright © 2018 Cloé Charpentier et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. C. Baumgart and S. R. Carding, “Inflammatory bowel disease: cause and immunobiology,” The Lancet, vol. 369, no. 9573, pp. 1627–1640, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. J. D. Lewis and M. T. Abreu, “Diet as a trigger or therapy for inflammatory bowel diseases,” Gastroenterology, vol. 152, pp. 398–414.e6, 2016. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Zallot, D. Quilliot, J. B. Chevaux et al., “Dietary beliefs and behavior among inflammatory bowel disease patients,” Inflammatory Bowel Diseases, vol. 19, no. 1, pp. 66–72, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. F. Bergeron, M. Bouin, L. D'Aoust, M. Lemoyne, and N. Presse, “Food avoidance in patients with inflammatory bowel disease: what, when and who?” Clinical Nutrition, 2017. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Shoda, K. Matsueda, S. Yamato, and N. Umeda, “Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan,” The American Journal of Clinical Nutrition, vol. 63, no. 5, pp. 741–745, 1996. View at Publisher · View at Google Scholar
  6. P. Jantchou, S. Morois, F. Clavel-Chapelon, M. C. Boutron-Ruault, and F. Carbonnel, “Animal protein intake and risk of inflammatory bowel disease: the E3N prospective study,” The American Journal of Gastroenterology, vol. 105, no. 10, pp. 2195–2201, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. J. K. Hou, B. Abraham, and H. El-Serag, “Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature,” The American Journal of Gastroenterology, vol. 106, no. 4, pp. 563–573, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Tasson, C. Canova, M. G. Vettorato, E. Savarino, and R. Zanotti, “Influence of diet on the course of inflammatory bowel disease,” Digestive Diseases and Sciences, vol. 62, no. 8, pp. 2087–2094, 2017. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Martinez-Medina, J. Denizot, N. Dreux et al., “Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation,” Gut, vol. 63, no. 1, pp. 116–124, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. T. L. Blasbalg, J. R. Hibbeln, C. E. Ramsden, S. F. Majchrzak, and R. R. Rawlings, “Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century,” The American Journal of Clinical Nutrition, vol. 93, no. 5, pp. 950–962, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. IBD in EPIC Study Investigators, A. Tjonneland, K. Overvad et al., “Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested casecontrol study within a European prospective cohort study,” Gut, vol. 58, no. 12, pp. 1606–1611, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. S. John, R. Luben, S. S. Shrestha, A. Welch, K. T. Khaw, and A. R. Hart, “Dietary n-3 polyunsaturated fatty acids and the aetiology of ulcerative colitis: a UK prospective cohort study,” European Journal of Gastroenterology & Hepatology, vol. 22, no. 5, pp. 602–606, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Rashvand, M. H. Somi, B. Rashidkhani, and A. Hekmatdoost, “Dietary fatty acid intakes are related to the risk of ulcerative colitis: a case–control study,” International Journal of Colorectal Disease, vol. 30, no. 9, pp. 1255–1260, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. P. S. A. de Silva, R. Luben, S. S. Shrestha, K. T. Khaw, and A. R. Hart, “Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries,” European Journal of Gastroenterology & Hepatology, vol. 26, no. 1, pp. 11–18, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. A. N. Ananthakrishnan, H. Khalili, M. Song et al., “High school diet and risk of Crohn’s disease and ulcerative colitis,” Inflammatory Bowel Diseases, vol. 21, no. 10, pp. 2311–2319, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Hassan, A. Ibrahim, K. Mbodji et al., “An α-linolenic acid-rich formula reduces oxidative stress and inflammation by regulating NF-ĸB in rats with TNBS-induced colitis,” The Journal of Nutrition, vol. 140, no. 10, pp. 1714–1721, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Ibrahim, M. Aziz, A. Hassan et al., “Dietary α-linolenic acid–rich formula reduces adhesion molecules in rats with experimental colitis,” Nutrition, vol. 28, no. 7-8, pp. 799–802, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Ibrahim, K. Mbodji, A. Hassan et al., “Anti-inflammatory and anti-angiogenic effect of long chain n-3 polyunsaturated fatty acids in intestinal microvascular endothelium,” Clinical Nutrition, vol. 30, no. 5, pp. 678–687, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Mbodji, C. Charpentier, C. Guérin et al., “Adjunct therapy of n-3 fatty acids to 5-ASA ameliorates inflammatory score and decreases NF-κB in rats with TNBS-induced colitis,” The Journal of Nutritional Biochemistry, vol. 24, no. 4, pp. 700–705, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Camuesco, M. Comalada, A. Concha et al., “Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis,” Clinical Nutrition, vol. 25, no. 3, pp. 466–476, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. D. Camuesco, J. Gálvez, A. Nieto et al., “Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis,” The Journal of Nutrition, vol. 135, no. 4, pp. 687–694, 2005. View at Google Scholar
  22. B. G. Feagan, W. J. Sandborn, U. Mittmann et al., “Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC randomized controlled trials,” JAMA, vol. 299, no. 14, pp. 1690–1697, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. R. Marion-Letellier, G. Savoye, P. L. Beck, R. Panaccione, and S. Ghosh, “Polyunsaturated fatty acids in inflammatory bowel diseases: a reappraisal of effects and therapeutic approaches,” Inflammatory Bowel Diseases, vol. 19, no. 3, pp. 650–661, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. H. Blanchard, F. Pédrono, N. Boulier-Monthéan, D. Catheline, V. Rioux, and P. Legrand, “Comparative effects of well-balanced diets enriched in α-linolenic or linoleic acids on LC-PUFA metabolism in rat tissues,” Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), vol. 88, no. 5, pp. 383–389, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Uchiyama, M. Nakamura, S. Odahara et al., “N-3 polyunsaturated fatty acid diet therapy for patients with inflammatory bowel disease,” Inflammatory Bowel Diseases, vol. 16, no. 10, pp. 1696–1707, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. M. de Lorgeril, P. Salen, J. L. Martin, I. Monjaud, J. Delaye, and N. Mamelle, “Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study,” Circulation, vol. 99, no. 6, pp. 779–785, 1999. View at Publisher · View at Google Scholar
  27. J. Bertrand, R. Marion-Letellier, S. Azhar et al., “Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity,” Proteomics, vol. 15, no. 13, pp. 2198–2210, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. J. M. Monk, H. F. Turk, Y.-Y. Fan et al., “Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity,” Mediators of Inflammation, vol. 2014, Article ID 917149, 14 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Marion-Letellier, G. Savoye, and S. Ghosh, “Polyunsaturated fatty acids and inflammation,” IUBMB Life, vol. 67, no. 9, pp. 659–667, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. A. Pupe, P. De Haes, L. Rhodes et al., “Eicosapentaenoic acid, a n-3 polyunsaturated fatty acid differentially modulates TNF-α, IL-1α, IL-6 and PGE2 expression in UVB-irradiated human keratinocytes,” Journal of Investigative Dermatology, vol. 118, no. 4, pp. 692–698, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. L. Anderson and J. Seilhamer, “A comparison of selected mRNA and protein abundances in human liver,” Electrophoresis, vol. 18, no. 3-4, pp. 533–537, 1997. View at Publisher · View at Google Scholar · View at Scopus
  32. H. W. Hsueh, Z. Zhou, J. Whelan et al., “Stearidonic and eicosapentaenoic acids inhibit interleukin-6 expression in ob/ob mouse adipose stem cells via toll-like receptor-2–mediated pathways,” The Journal of Nutrition, vol. 141, no. 7, pp. 1260–1266, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. R. K. Murumalla, M. K. Gunasekaran, J. K. Padhan et al., “Fatty acids do not pay the toll: effect of SFA and PUFA on human adipose tissue and mature adipocytes inflammation,” Lipids in Health and Disease, vol. 11, no. 1, p. 175, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. S. Ghosh, D. DeCoffe, K. Brown et al., “Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis,” PLoS One, vol. 8, no. 2, article e55468, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. H. Ohmori, Y. Luo, K. Fujii et al., “Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1,” Pathobiology, vol. 77, no. 4, pp. 210–217, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. H. E. Harris, U. Andersson, and D. S. Pisetsky, “HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease,” Nature Reviews Rheumatology, vol. 8, no. 4, pp. 195–202, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. T. Shimomoto, Y. Luo, H. Ohmori et al., “Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet,” Journal of Gastroenterology, vol. 47, no. 10, pp. 1073–1083, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. N. Nieto, M. I. Torres, A. Rios, and A. Gil, “Dietary polyunsaturated fatty acids improve histological and biochemical alterations in rats with experimental ulcerative colitis,” The Journal of Nutrition, vol. 132, no. 1, pp. 11–19, 2002. View at Google Scholar
  39. J. Bassaganya-Riera and R. Hontecillas, “CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD,” Clinical Nutrition, vol. 25, no. 3, pp. 454–465, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. S. Dhe-Paganon, K. Duda, M. Iwamoto, Y. I. Chi, and S. E. Shoelson, “Crystal structure of the HNF4α ligand binding domain in complex with endogenous fatty acid ligand,” Journal of Biological Chemistry, vol. 277, no. 41, pp. 37973–37976, 2002. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Darsigny, J.-P. Babeu, A.-A. Dupuis et al., “Loss of hepatocyte-nuclear-factor-4α affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice,” PLoS One, vol. 4, no. 10, article e7609, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. R. Marion-Letellier, M. Butler, P. Dechelotte, R. J. Playford, and S. Ghosh, “Comparison of cytokine modulation by natural peroxisome proliferator–activated receptor γ ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells—potential for dietary modulation of peroxisome proliferator–activated receptor γ in intestinal inflammation,” The American Journal of Clinical Nutrition, vol. 87, no. 4, pp. 939–948, 2008. View at Google Scholar
  43. R. Marion-Letellier, P. Dechelotte, M. Iacucci, and S. Ghosh, “Dietary modulation of peroxisome proliferator-activated receptor gamma,” Gut, vol. 58, no. 4, pp. 586–593, 2009. View at Publisher · View at Google Scholar · View at Scopus
  44. C. A. Hudert, K. H. Weylandt, Y. Lu et al., “Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 30, pp. 11276–11281, 2006. View at Publisher · View at Google Scholar · View at Scopus
  45. T. Grimstad, R. K. Berge, P. Bohov et al., “Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-inflammatory fatty acid index – a pilot study,” Scandinavian Journal of Clinical and Laboratory Investigation, vol. 71, no. 1, pp. 68–73, 2011. View at Publisher · View at Google Scholar · View at Scopus