Restoring Inflammatory Mediator Balance after Sofosbuvir-Induced Viral Clearance in Patients with Chronic Hepatitis C

Table 4

Correlation between cytokines and noninvasive methodologies for liver injury measure.

		ALT	Albumin	APRI	FIB-4	FibroScan
CCL-2	r	−0.028	−0.057	0.060	0.351	0.466
		NS	NS	NS	NS	NS
CCL-3	r	−0.250	0.241	−0.264	−0.194	−0.310
		NS	NS	NS	NS	NS
CCL-4	r	0.143	−0.029	−0.080	0.071	0.063
		NS	NS	NS	NS	NS
CCL-5	r	0.043	0.041	0.119	0.146	0.199
		NS	NS	NS	NS	NS
CCL-11	r	0.040	−0.454	0.032	0.066	0.135
		NS	0.005	NS	NS	NS
CXCL-8	r	−0.020	−0.182	0.229	0.420	0.018
		NS	NS	NS	NS	NS
CXCL-10	r	0.029	−0.050	−0.052	−0.012	−0.235
		NS	NS	NS	NS	NS
IFN-γ	r	0.294	−0.058	0.070	0.041	−0.019
		NS	NS	NS	NS	NS
IL-1β	r	0.148	−0.201	0.225	0.258	0.249
		NS	NS	NS	NS	NS
IL-2	r	0.457	−0.521	0.451	0.577	−0.027
		NS	NS	NS	0.039	NS
IL-6	r	−0.228	−0.311	0.048	0.381	−0.190
		NS	NS	NS	NS	NS
IL-7	r	0.500	0.355	0.429	0.250	0.500
		NS	NS	NS	NS	NS
IL-15	r	0.535	−0.298	0.495	0.438	−0.066
		0.04	NS	NS	NS	NS
IL-4	r	0.195	−0.085	0.042	−0.079	−0.095
		NS	NS	NS	NS	NS
IL-10	r	0.250	0.000	−0.100	−0.183	−0.204
		NS	NS	NS	NS	NS
IL-1ra	r	0.178	−0.111	0.196	0.204	0.289
		NS	NS	NS	NS	NS
TGF-β	r	−0.043	0.281	−0.395	−0.521	−0.351
		NS	NS	0.017	0.001	NS
CSF-3	r	0.494	−0.162	0.213	0.231	0.144
		NS	NS	NS	NS	NS
FGFb	r	0.040	0.295	−0.154	−0.138	−0.195
		NS	0.026	NS	NS	NS
PDGF-BB	r	0.024	0.328	−0.319	−0.365	−0.330
		NS	NS	NS	0.028	NS
VEGF	r	0.118	0.036	0.168	0.189	0.154
		NS	NS	NS	NS	NS
PAI-1	r	0.161	−0.238	0.026	−0.061	−0.069
		NS	NS	NS	NS	NS
suPAR	r	0.089	−0.531	0.350	0.424	0.542
		NS	0.001	0.037	0.010	0.001

r: Spearman’s or Pearson’s coefficients for non-parametric and parametric parameters, respectively. NS: nonsignificant. : indicate significant value < 0.05. The bold numbers indicate values < 0.05.