Whole-Body Cryotherapy Decreases the Levels of Inflammatory, Oxidative Stress, and Atherosclerosis Plaque Markers in Male Patients with Active-Phase Ankylosing Spondylitis in the Absence of Classical Cardiovascular Risk Factors
Table 6
Levels of lipid profile parameters, atherosclerosis plaque markers, and atherosclerosis plaque instability and values of TG/HDL ratio (mean value ± standard deviation (SD)) in AS patients before and after the completion of a cycle of ten whole-body cryotherapy procedures with subsequent kinesiotherapy (WBC group) or a cycle of ten kinesiotherapy procedures only (KT group), with statistical analyses. (p): plasma; (s): serum; (e): erythrocyte lysates; Δ: difference prior to post treatment.
Parameters
WBC group
KT group
T-Chol (s) (mg/dl)
Before
221.3 ± 39.17
200.33 ± 21.33
0.074
After
202.40 ± 24.40
190.70 ± 22.57
0.51
0.0006
0.04
Δ
−18.90 ± 20.54
−9.63 ± 18.38
0.20
LDL-Chol (s) (mg/dl)
Before
125.2 ± 32.6
145.3 ± 28.3
0.073
After
93.3 ± 36.9
132.4 ± 24.7
0.002
<0.001
0.005
Δ
−31.9 ± 28.6
−12.9 ± 15.1
0.027
HDL-Chol (s) (mg/dl)
Before
50.5 ± 14.1
58.0 ± 18.0
0.198
After
47.0 ± 9.0
56.4 ± 18.2
0.078
0.079
0.109
Δ
−3.5 ± 9.1
−1.7 ± 10.1
0.590
TG (s) (mg/dl)
Before
185.1 ± 18.9
178.6 ± 15.9
0.299
After
156.7 ± 11.2
165.2 ± 20.4
0.158
0.001
0.001
Δ
−28.4 ± 22.4
−13.4 ± 19.7
0.053
TG/HDL ratio
Before
3.95 ± 1.18
3.32 ± 0.96
0.150
After
3.44 ± 0.60
3.18 ± 0.99
0.320
0.055
0.250
Δ
−0.51 ± 0.92
−0.14 ± 0.43
0.190
sCD40L(s) (mg/ml)
Before
9.21 ± 3.88
7.25 ± 2.20
0.180
After
5.01 ± 2.55
5.85 ± 2.06
0.171
0.0004
0.006
Δ
−4.19 ± 2.17
−1.4 ± 1.78
0.0001
PLGF(s) (pg/ml)
Before
30.17 ± 10.23
21.69 ± 3.54
0.007
After
19.32 ± 5.53
18.31 ± 2.91
0.641
0.001
0.004
Δ
−10.84 ± 7.05
−3.38 ± 2.13
0.0001
PAPP-A (s) (ng/ml)
Before
17.74 ± 7.78
14.48 ± 4.52
0.162
After
11.24 ± 3.12
11.79 ± 3.72
0.920
0.0004
0.003
Δ
−6.51 ± 8.40
−2.69 ± 3.65
0.008
: statistical significance of differences between both groups of patients; : statistical significance of differences between values before and after treatment in particular groups of patients.
