CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages

Figure 7

Chemokine secretions are regulated by CD38 in macrophages. An expression profile of chemokine proteins was obtained by performing a chemokine antibody array with WT, the negative control dCas9, and the CD38 knockdown clones E1a and E3 RAW264.7 cells (a). Template showing the location of chemokine antibodies spotted onto the RayBio chemokine array (b). Mean optic densities of protein were calculated by normalizing to positive controls, and results were compared (c). The data represent the . from three independent experiments. and compared with the dCas9 group.

(a)

(b)

(c)