The Associations between Toll-Like Receptor 9 Gene Polymorphisms and Cervical Cancer Susceptibility

Table 3

Meta-analysis results of rs352140 based on five genetic models.

Genetic models	OR (95% CI)	p value	Heterogeneity		Effects model
			I ^2 (%)	p value
Allele model (A versus G)
Overall	1.20 (0.97, 1.47)	0.09	83	0.00001	R
Race
Chinese Han	1.46 (0.86, 2.48)	0.16	91	<0.0001	R
Caucasian	1.11 (1.01, 1.22)	0.03	0	0.62	R
Dominant model (AA + GA versus GG)
Overall	1.30 (0.97, 1.74)	0.08	73	0.001	R
Race
Chinese Han	1.54 (0.91, 2.61)	0.11	83	0.0006	R
Caucasian	1.17 (0.91, 1.49)	0.22	17	0.30	R
Recessive model (AA versus GA + GG)
Overall	1.23 (0.81, 1.86)	0.34	77	0.0002	R
Race
Chinese Han	1.35 (0.54, 3.39)	0.52	87	<0.0001	R
Caucasian	1.20 (0.94, 1.51)	0.14	0	0.39	R
Heterozygous genetic model (GA versus GG)
Overall	1.24 (0.96, 1.59)	0.10	58	0.03	R
Race
Chinese Han	1.42 (0.94, 2.15)	0.09	67	0.03	R
Caucasian	1.09 (0.81, 1.49)	0.56	38	0.20	R
Homozygous genetic model (AA versus GG)
Overall	1.34 (0.83, 2.15)	0.23	78	0.0001	R
Race
Chinese Han	1.53 (0.57, 4.15)	0.40	88	<0.0001	R
Caucasian	1.30 (0.98, 1.73)	0.07	0	0.42	R

F: fixed-effect model; R: random-effect model; OR: odds ratio; 95% CI: 95% confidence interval.