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Mediators of Inflammation

Mediators of Inflammation / 2018 / Article / Tab 2

Research Article

Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis

Table 2

TLR10 expression in B cells and B cell subsets in the study subjects.
Control ()RA ()LA ()MA ()HA ()#
CD19+       
 %51.4 ± 2.453.0 ± 1.70.61243.8 ± 2.051.9 ± 2.560.2 ± 2.90.001
 MFI17.5 ± 0.417.5 ± 0.30.90816.2 ± 0.217.1 ± 0.418.7 ± 0.60.03
CD19+CD27+       
 %73.3 ± 2.272.7 ± 1.60.82967.1 ± 3.372.2 ± 7.476.8 ± 2.60.038
 MFI22.7 ± 1.022.8 ± 0.60.93220.8 ± 0.721.8 ± 0.725.1 ± 1.30.093
CD19+CD27−       
 %43.7 ± 2.446.5 ± 1.80.38536.8 ± 2.445.2 ± 2.354.2 ± 3.20.001
 MFI15.4 ± 0.315.9 ± 0.20.20720.8 ± 0.715.6 ± 0.316.9 ± 0.5≤0.001
CD19+CD27+IgD−       
 %78.3 (60.6-83.5)74.5 (61.5-84.3)0.91462.1 (58.6-78.8)74.8 (62.0-80.8)80.1 (65.3-87.3)0.054
 FI22.5 (19.0-25.1)21.9 (19.5-25.0)0.81920.4 (18.4-22.9)21.7 (19.2-25.2)22.1 (20.2-31.1)0.097
CD19+CD27+IgD+       
 %72.3 (55.8-81.4)72.2 (61.0-84.6)0.47970.0 (53.9-78.3)69.4 (57.8-83.5)77.6 (67.8-88.5)0.026
 FI18.8 (17.5-22.6)20.6 (17.9-24.2)0.27618.3 (16.4-22.1)19.8 (18.1-25.8)21.9 (18.5-26.1)0.101
CD19+CD27−IgD+       
 %43.8 (33.9-55.0)43.4 (35.1-55.4)0.73738.9 (28.2-41.9)43.5 (37.5-53.1)54.4 (38.9-68.6)0.001
 FI15.4 (14.1-16.4)15.0 (13.9-16.4)0.60514.1 (13.8-14.6)15.5 (14.0-15.9)15.7 (14.6-18.1)0.002
CD19+CD27−IgD−       
 %40.5 (26.4-49.8)42.8 (35.0-62.2)0.04736.7 (26.1-46.4)41.6 (33.5-61.8)54.5 (39.0-67.9)0.016
 MFI16.7 (15.0-18.3)17.0 (15.3-20.4)0.16716.3 (15.3-17.2)18.1 (15.1-20.7)18.3 (15.7-21.7)0.126
CD19+CD5+       
 %34.6 (25.7-46.8)44.3 (33.2-54.0)0.02436.0 (30.5-44.2)44.3 (32.6-52.8)52.0 (42.7-68.0)0.002
 MFI16.1 (14.1-17.0)16.1 (14.6-17.5)0.39714.6 (14.2-16.8)16.4 (15.2-17.3)16.5 (15.0-18.6)0.034
CD19+CD5−       
 %52.1 (36.2-63.4)45.0 (34.9-59.0)0.43541.1 (35.0-45.4)41.9 (30.7-58.2)51.7 (39.4-67.6)0.033
 MFI16.9 (15.5-19.0)16.5 (15.3-18.5)0.30415.8 (15.0-17.2)15.8 (15.0-19.0)16.8 (15.8-18.9)0.098
The data are shown as the means ± SE or median (interquartile range, 25th-75th). represents a comparison between the RA subjects and HCs based on the Mann–Whitney test. # represents a comparison among the three groups of RA subjects based on the Kruskal–Wallis test.