Review Article
Single Nucleotide Polymorphism in SMAD7 and CHI3L1 and Colorectal Cancer Risk
Table 12
Association studies of SNPs in SMAD7 gene and CRC.
| Population | Reference SNP (rs) | Location | Association | Reference |
| African American and Caucasian | rs4939827 | Intron 3 | In women: yes | [166] | rs4464148 | Intron 3 | Yes | Caucasian | rs12953717 | Intron 3 | Yes | [167] | rs4939827 | Intron 3 | Yes | rs4464148 | Intron 3 | No | Swedish | rs4939827 | Intron 3 | Yes | [168] | European | rs4464148 | Intron 3 | Yes | [169] | rs4939827 | Intron 3 | No | Chinese | rs4939827 | Intron 3 | No | [170] | rs12953717 | Intron 3 | Yes | rs4464148 | Intron 3 | No | African American | rs4939827 | Intron 3 | Yes | [171] | Chinese | rs4939827 | Intron 3 | Yes | [76] | Romanian | rs4939827 | Intron 3 | CRC vs control: no
| [172] | Rectal vs colon cancer: yes | Caucasian | rs4939827 | Intron 3 | Yes | [173] | Croatian | rs4939827 | Intron 3 | Yes | [77] | Italian | rs4939827 | Intron 3 | Yes | [174] | Korean | rs4939827 | Intron 3 | Yes | [175] | Spanish | rs4939827 | Intron 3 | Yes | [176] | French | rs4939827 | Intron 3 | Yes | [177] | rs58920878 | Intron 3 | Yes |
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