HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-<i>γ</i> Signalling Pathway

<div>PPAR-<i>γ</i> activation on the SOCS/JAK2/STAT/PPAR-<i>γ</i> pathway. RAW264.7 cells were preincubated with rosiglitazone (RSG) (1 <i>μ</i>mol/mL) or T0070907 (1 <i>μ</i>mol/mL) for 3 h, followed by combined treatment with either the control DMEM solution, LPS+IFN-<i>γ</i>, IL-4, or HuoXueTongFu Formula (HXTF) treatment for 12 h. The protein expression was assayed by Western blotting. (a) RSG administration on the SOCS/JAK2/STAT/PPAR-<i>γ</i> pathway. (b) T0070907 administration on the SOCS/JAK2/STAT/PPAR-<i>γ</i> pathway. 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Mediators of Inflammation

fig7

Figure 7

Figure 7: HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-<i>γ</i> Signalling Pathway 

Figure 7 | HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway 