Research Article
Chemokine Receptor 2 (CXCR2) Gene Variants and Their Association with Periodontal Bacteria in Patients with Chronic Periodontitis
Table 2
CXCR2 genotype and allele frequencies in CP patients and healthy nonperiodontitis controls.
| | Genotypes | Controls | CP | value | OR (95% CI) | | Alleles | (%) | (%) |
| | CXCR2 +785 | | | | | | CC | 41 (24.0) | 81 (24.6) | — | 1.00 | | CT | 93 (54.4) | 166 (50.5) | 0.37 | 0.90 (0.57-1.42) | | TT | 37 (21.6) | 82 (24.9) | 0.39 | 1.12 (0.65-1.93) | | C allele | 175 (51.2) | 328 (49.8) | — | 1.00 | | T allele | 167 (48.8) | 330 (50.2) | 0.37 | 1.05 (0.81-1.37) |
| | CXCR2 +1208 | | | | | | CC | 45 (26.3) | 91 (27.7) | — | 1.00 | | CT | 90 (52.6) | 174 (52.9) | 0.47 | 0.96 (0.62-1.48) | | TT | 36 (21.1) | 64 (19.5) | 0.37 | 0.88 (0.51-1.51) | | C allele | 180 (52.6) | 356 (54.1) | — | 1.00 | | T allele | 162 (47.4) | 302 (45.9) | 0.35 | 0.94 (0.73-1.22) |
| | CXCR2 +1440 | | | | | | AA | 35 (20.5) | 59 (17.9) | — | 1.00 | | AG | 89 (52.0) | 171 (52.0) | 0.34 | 1.14 (0.70-1.86) | | GG | 47 (27.5) | 99 (30.1) | 0.25 | 1.25 (0.73-2.15) | | A allele | 159 (46.5) | 289 (43.9) | — | 1.00 | | G allele | 183 (53.5) | 369 (56.1) | 0.24 | 1.11 (0.85-1.44) |
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CI = confidential interval; CP = chronic periodontitis; = number of subjects; OR = odds ratio. |
