METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway

Figure 1

Expression of m⁶A methylation-related genes in RA (cases/controls: 47/30). (a) Increased mRNA level of METTL3 in RA in contrast to healthy controls. (b) mRNA level of METTL14 in RA when comparing with healthy controls. (c) mRNA level of FTO in RA compared with healthy controls. (d) mRNA level of ALKBH5 in RA in contrast to healthy controls. (e) mRNA level of YTHDF1 in RA when comparing with healthy controls. (f) mRNA level of YTHDF2 in RA in contrast to healthy controls. (g) Increased mRNA level of METTL3 in monocytes of RA patients in contrast to controls. (h) Increased METTL3 protein in monocytes of RA patients in contrast to controls.

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