Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality

Table 3

Correlations between PTX3 and other inflammatory markers, with each other, and cardiac and renal fibrosis markers, in end-stage renal disease patients.

		PTX3	hsCRP	IL-6	TNF-α
Inflammatory markers
hsCRP		0.157	—	—	—
		0.013
IL-6		0.197	0.583	—	—
		0.002	<0.001
TNF-α		0.142	0.259	0.277	—
		0.026	<0.001	<0.001
Cardiac marker
NT-proBNP		0.344	0.191	0.281	0.120
		<0.001	0.003	<0.001	0.061
Tubular injury marker
TIMP-1		0.281	0.270	0.268	0.105
		<0.001	<0.001	<0.001	0.101

r_S: Spearman’s rank correlation coefficient; PTX3: pentraxin 3; hsCRP: high-sensitivity C-reactive protein; IL-6: interleukin-6; TNF-α: tumor necrosis factor-alpha; NT-proBNP: N-terminal pro-B-type natriuretic peptide; TIMP-1: tissue inhibitor of metalloproteinase-1.