Involvement of Oxidative Stress and the Epidermal Growth Factor Receptor in Diesel Exhaust Particle-Induced Expression of Inflammatory Mediators in Human Mononuclear Cells

Figure 2

DEP exposure induces overexpression of proinflammatory mediators in THP-1 cells. THP-1 cells were incubated with 10-100 μg/ml DEP for 24 h, respectively. The supernatants of cell culture media were collected through centrifuge. Levels of IL-8 (a) or TNFα (b) were measured using ELISA. , compared with 0 μg/ml DEP, .

(a)

(b)