Coronary Artery Disease Is Associated with an Increased Amount of T Lymphocytes in Human Epicardial Adipose Tissue

Figure 2

Different lymphocyte populations in peripheral blood and subcutaneous and epicardial adipose tissues of subjects with and without coronary artery disease—flow cytometry. (a) Total lymphocytes (CD45+ cells), (b) T lymphocytes (CD3+ CD45+ cells), (c) CD3- cells (CD3-CD45+ cells), (d) T helper lymphocytes (CD4+CD3+CD45+ cells), (e) T cytotoxic lymphocytes (CD8+CD3+CD45+ cells), (f) NKT cells (CD16/56+CD3+CD45+ cells), (g) B lymphocytes (CD19+CD3-CD45+ cells), and (h) NK cells (CD16/56+CD3-CD45+ cells). CD45+ cells are represented as the percentage of single cells; all other cell subtypes are represented as the percentage of CD45+ cells. Circles represent individual subjects while bars show . ^X vs. without CAD, ^S vs. subcutaneous adipose tissue. SAT: subcutaneous adipose tissue; EAT: epicardial adipose tissue; non-CAD subjects: white circles; CAD subjects: grey circles.

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