(a)
(b)
Figure 5: Regulation of Akt and GSK3β by IL-4 in muscle under insulin resistance and diabetic status. (a) Results of Western blotting showing the alternations of p-Akt and p-GSK-3β in quadriceps tissues obtained from STZ-induced diabetic mice administered with adenovirus containing full-length IL-4 (AdIL-4 mice) mice receiving IL-4 injection (HFD + IL-4 mice). v.s control, p < 0.05 v.s AdLacZ, n = 3-5. (b) Western blotting showing the alternations of p-Akt and p-GSK-3β in quadriceps tissues obtained from obesity-induced insulin resistant mice receiving IL-4 injection (HFD + IL-4 mice). v.s control,p < 0.05 v.s IL-4, p < 0.05 v.s HFD; n = 3-4.