Curcumin Attenuates Asthmatic Airway Inflammation and Mucus Hypersecretion Involving a PPARγ-Dependent NF-κB Signaling Pathway In Vivo and In Vitro
Curcumin suppressed MCP-1 and MUC5AC expression in IL-4-induced BEAS-2B cells. (a and c) qPCR was used to measure MCP-1 and MUC5AC mRNA expression in BEAS-2B cells; (b and d) western blotting was performed to measure MCP-1 and MUC5AC protein expression in BEAS-2B cells. Quantitative data were presented as (). compared with control. compared with IL-4. compared with IL-4 + Cur + shRNA-PPARγ.