Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection

Figure 2

HMPV-mediated expression of the antiviral genes IFN-β, IFN-λ1, IFN-λ2/3, and ISG54 in airway epithelial and immune cells. Cells were infected with HMPV for the indicated time points. Gene expression was analyzed by qRT-PCR. Expression was normalized relative to GAPDH. Data are presented as of 3 (a) or 2 (b-d) independent experiments. (a) A549, (b) NEC, (c) MDM, and (d) MDDC. (a-d) Statistical analysis (one-sided ANOVA with Dunnett’s test): (), (), and (); comparisons were made between noninfected and infected cells.

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