Mediators of Inflammation

Research Article

The Role of Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Table 2

Clinical characteristics.


		AE-IPF ()	Stable IPF ()	Control ()

Gender	Male	48/48 (100%)	110/122 (90.2%)	63/70 (90%)
Gender	Female	0/48	12/122 (9.8%)	7/70 (10%)
Age (yr)
Environmental exposure^a		8/48 (16.7%)	26/122 (21.3%)	6/70 (8.6%)
Surgical lung biopsy^b		0	5	/
Smoking (%)		70.8	68.9	28.6
History of recent cold (%)		89.6	13.1	0
Family history		0	1	0
1-year mortality		19/48 (39.5%)	35/122 (28.7%)	0
WBC (×10⁹/L)
Neutrophils (%)
Lymphocytes (%)
Monocytes (%)
pH				NA
PaCO₂ (mmHg)				NA
PaO₂ (mmHg)				NA
SaO₂ (%)				NA
FVC (% predicted)				NA
FEV1 (% predicted)				NA
FEV1/FVC				NA
TLC (% predicted)				NA
RV/TLC				NA
DLco (% predicted)				NA
HRCT scores				NA

vs. stable IPF; vs. control. Patients were engaged in mining, painting, chemical manufacturing, teaching, carpentry, welding, warehouse managing, and farming. 5 subjects were diagnosed with IPF by biopsy. Abbreviations: WBC: white blood cell; PaCO₂: carbon dioxide partial pressure; PaO₂: oxygen partial pressure; SaO₂: oxygen saturation; FVC: forced vital capacity; FEV1: 1 second forced expiratory volume; TLC: total lung capacity; DLco: diffusion capacity for carbon monoxide; HRCT: high-resolution computed tomography; NA: not available.