PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes

<div>Silencing of <i>IL37</i> augments inflammatory responses to cytokines in HaCaT cells. (a) siRNA-mediated knockdown of <i>IL37</i> was confirmed by Western blot analysis. (b) HaCaT cells were transfected with the control and <i>IL37</i> siRNAs and treated with the mixture of five cytokines (M5) for 24 hours, followed by RT-qPCR analysis. Representative results from three independent experiments are shown. 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Mediators of Inflammation

fig1

Figure 1

Figure 1: PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes 