Mediators of Inflammation / 2019 / Article / Fig 2

Research Article

Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs

Figure 2

Andr attenuates HG-induced cell migration and impairment of angiogenesis in HUVECs. (a, b) In the scratch assay, HUVECs were treated with Andr (50 μM) and/or HG for 24 hours and photographed at 0, 12, and 24 hours (). (c, d) In the tube formation assay, HUVECs were treated with Andr (50 μM) and/or HG. After 24 hours, images were acquired by inverted microscopy, and the results were analysed in each group (). (e, f) The expression of VEGF protein and the quantitative analysis in each group (). vs. the control group. # vs. the HG group.

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