PPAR-γ Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons

Figure 4

(a) Representative Western blots showing the effects of rosiglitazone on caspase-1, NF-κB, and NLRP3 of sham, control, rosiglitazone, G3335, and rosiglitazone+MSU groups. (b) Relative caspase-1 and NF-κB protein levels in sham, control, and rosiglitazone groups. (c) Relative caspase-1 and NLRP3 protein levels in sham, control, rosiglitazone, and G3335 groups. (d) Relative caspase-1 protein levels in sham, control, rosiglitazone, and rosiglitazone+MSU groups. (e, f) IL-1β and IL-6 expression levels in sham, control, and rosiglitazone groups. (g, h) IL-1β and IL-6 expression levels in sham, control, rosiglitazone, and G3335 groups. (i, j) IL-1β and IL-6 expression levels in sham, control, rosiglitazone, and rosiglitazone+MSU groups. Data are expressed as ().

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