IL-17 Inversely Correlated with IL-10 via the STAT3 Gene in Pneumocystis-Infected Mice

Figure 4

IL-17 inversely interplayed with IL-10 in the PCP model. Representative flow cytometric dot plots and comparisons of B10 cells (CD19⁺IL-10⁺) (a), IL-10⁺ macrophages (F4/80⁺IL-10⁺) (b), and IL-10⁺ T cells (CD4⁺IL-10⁺) (c) in the lungs from WT PCP mice and IL-17 PCP mice. Representative flow cytometric dot plots and comparisons of Th17 cells (CD4⁺IL-17⁺) (d) and IL-17⁺γδT cells (γδT⁺IL-17⁺) (e) in the lungs from WT PCP mice and IL-10 PCP mice. . Comparisons were evaluated by Student’s -test for two-group comparisons. WT: wild type; PCP: Pneumocystis pneumonia.