NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs
Suppression of CaSR prevented aortic fibrosis in SHRs. (a) Masson staining was used to detect aortic fibrosis, bar = 50 μm, . (b) Quantification of the fibrosis area to vascular area of these arteries. (c) Western blots of collagen I, collagen III, MMP2, MMP9, and TIMP2 expressions. (d–h) Quantitative analyses of the proteins from C. and vs. WKY; ,, and vs. SHRs.