Research Article

Relation of Macrophage Migration Inhibitory Factor to Pulmonary Hemodynamics and Vascular Structure and Carbamyl-Phosphate Synthetase I Genetic Variations in Pediatric Patients with Congenital Cardiac Shunts

Figure 2

Serum MIF levels in patient groups according to the clinical/hemodynamic presentation (a) and carbamyl-phosphate synthetase I (CPSI) T1405N polymorphism (b, c, d). Despite a relatively small number of subjects for the subgroup analysis, specific data for the subgroups with (d) and without Down syndrome (c) are presented. In all graphs, the bars represent the estimated marginal means with SE after adjustment for age. Means not sharing the same letter were significantly different by post hoc multiple comparison tests. PBF and PVR, pulmonary blood flow and pulmonary vascular resistance, respectively. CC and AC, CPSI T1405N genotypes present in the study population.
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