The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood

Table 1

Patient characteristics.

Characteristic	Result
Total number of patients	245
Male sex (%)	140/245 (57.1)
Age, median months (IQR)	8 (5–19)
Duration of preadmission illness, median days (IQR)	2 (1–3)
GCS score on admission, median (IQR)	13 (11–14)
Etiology, number of cases (%)
Haemophilus influenzae	122 (49.8)
Streptococcus pneumoniae	64 (26.1)
Neisseria meningitidis	10 (4.1)
Other	12 (4.9)
Unknown	37 (15.1)
CSF test results on admission
Leukocyte count, median cells/μL (IQR)	2,500 (900–8,050)
Protein level, median mg/dL (IQR)	158 (94–257)
Glucose level, median mg/dL (IQR)	15 (6–32)
Disease outcomes, number of patients
Death (%)	33/245 (13.5)
Death or severe neurological sequelae (%)	58/242^a (24.0)
Death or any neurological sequelae (%)	112/241^b (46.5)

IQR: interquartile range. ^aInformation on severe neurological sequelae was missing for 3 patients. ^bInformation on any neurological sequelae was missing for 4 patients.