Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between β2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells
Effect of agonists on the expression of β2-AR and TLR4 in HPMECs. (a) Effect of agonists on the cell surface expression of proteins in HPMECs. The representative blots show the expression of β2-AR (A, upper), TLR4 (A, middle), and Na+-K+-ATPase (A, lower). The histograms illustrate the quantitative analysis of the β2-AR and TLR4 protein levels normalized to Na+-K+-ATPase. (b, c) Expression of inflammatory factors (IL-6, IL-17A, IL-8, and TNF-α) after treatment with ISO and LPS. (d) Effect of ISO and LPS treatment on monolayer permeability. The data are the (). versus the blank group; ^ versus the LPS group; #versus the ISO group.
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