Elevation of IL-6 and IL-33 Levels in Serum Associated with Lung Fibrosis and Skeletal Muscle Wasting in a Bleomycin-Induced Lung Injury Mouse Model

Figure 2

Lung function was reduced in mice with BLM-induced fibrotic lungs. Anesthetized mice were endotracheally intubated with an airway catheter, and the parameters of lung function were measured by a pulmonary function testing system. (a) FVC (forced vital capacity), (b) IC (inspiratory capacity), (c) VC (vital capacity), (d) FRC (functional residual capacity), (e) TLC (total lung capacity), and (f) C chord (lung compliance). The quantitative data were expressed as the . Light spots represent the lung function of control mice (), and dark spots represent the lung function of mice with BLM-induced lung injury (). and compared with control mice.

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