Table 2: Effects of LCFAs on immunity cells in IBD.

Effects of LCFAs on immune cellsThe type of LCFAsRole

Neutrophilsn-6 PUFAsInhibit neutrophil infiltration
DHA and EPAInhibit neutrophil infiltration
n-3 PUFAsAvert the concomitant hurt caused by neutrophil production
Dendritic cellsn-3 PUFAsReduce the antigen-presenting ability of DCs
PGE2Promote the antigen-presenting ability of DCs
B cellsPalmitic acid and oleic acidReduce the immune response ability of B cells
n-3 PUFAsReduce the immune response ability of B cells, promote intestinal sIgA secretion
T cellsDFOReduce the percentage of CD8+ cells, diminish the expression of CD69 on CD4+ T cells, and increase the count of FoxP3+ CD25+ T cells
n-3 PUFAsReduce the activated cytokines of Th17 cells
EicosanoidsDecrease the percentage of Th17 cells