Identification of the Transcriptional Networks and the Involvement in Angiotensin II-Induced Injury after CRISPR/Cas9-Mediated Knockdown of Cyr61 in HEK293T Cells

Table 5

The top 10 most significant up- and downregulated mRNAs.

value	Gene symbol	Fold change (log FC)		Gene symbol	value
		Upregulation	Downregulation
5.10	FRMD1	2.6979	-2.020	PRR21	0.0039
4.62	SERPINF1	2.4507	-2.008	REG3G	0.0022
4.47	FEZ1	2.2722	-1.851	ACAT2	0.0006
1.50	CRABP2	2.2282	-1.701	PIGW	3.57
6.45	G0S2	2.2042	-1.698	RBM19	0.0019
4.76	CDA	2.1142	-1.674	RPL27A	6.55
1.29	TXNIP	2.0500	-1.623	ATF5	7.15
9.71	PADI2	2.0345	-1.610	ADI1	2.93
0.0001	SERPINF1	2.0129	-1.581	ADI1	7.22
1.27	CRABP2	1.9778	-1.565	UBAP2L	0.0138