Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny

Figure 8

LPS-stimulated ex vivo cytokine responses of splenocytes from control vs. LPS-affected mice across two generations of offspring. IFN-γ (a), IL-1β (b), IL-6 (c), TNF-α (d), and IL-10 (e) levels were analysed after 18-hour incubation with LPS. Two-way ANOVA and Fisher’s post hoc tests were used to compare LPS and saline groups. Data is represented , per group. Significance is depicted as follows: ; ; , and .

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