Review Article

Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the Course and Prognosis of Inflammatory Conditions

Table 1

Increased MPV in various diseases [226].

↑MPV in cardiovascular diseases
Endler et al. 2002 [2]Associated with a higher risk of acute cardiac incidents
Slavka et al. 2011 [3]Independent high risk factor of death in patients after acute ischemic cardiac incident
Huczek et al. 2005 [4]Related to the increased mortality rate in a six-month-period after the transdermal cardiac intervention
Shah et al. 2013 [5]Associated with higher risk of death within a long time after the transdermal cardiac intervention
MPV in cerebral stroke
D'Erasmo et al. 1990 [6]Increased MPV after stroke was related to higher mortality
Greisenegger et al. 2004 [7]Associated with a risk of acute stroke
O’Malley et al. 1995 [8]MPV as a prognostic marker in patients after stroke characteristic for acute and nonacute phases of cerebral ischemia
MPV in respiratory diseases
Feng et al. 2011 [9]
Unsal et al. 2005 [10]
In tuberculosis associated with intensity of inflammation
Koç et al. 2011 [11]Associated with the development and course of the chronic sinusitis
MPV in chronic renal failure
Sharpe et al. 1994 [12]In patients treated with recombinant erythropoietin (HuEPO) leading to higher risk of blood clot formation
MPV in intestine diseases
Liu et al. 2012 [13]Differentiate patients with Crohn’s disease from healthy subjects
Zubcevic et al. 2010 [14]Marker of the Crohn’s disease activity
MPV in rheumatoid diseases
Gasparyan et al. 2010 [15]In rheumatoid arthritis, increased MPV is observed due to administration of anti-inflammatory drugs
Yavuz and Ece 2014 [16]Correlated with the advancement of juvenile SLE
MPV in diabetes
Papanas et al. 2004 [17]Associated with retinopathy and nephropathy
Rollini et al. 2013 [18]Responsible for increased risk of diabetes and worse outcome
MPV in carcinomas
Kurt et al. 2012 [19]Potential marker of liver cancer in patients with chronic liver diseases
Li et al. 2017 [20]In colorectal cancer patients compared to healthy subjects
Tunce et al. 2014 [21]In colorectal cancer patients with metastases compared to nonmetastatic colorectal cancer patients
Kılınçalp et al. 2014 [22]In primary gastric cancer patients preoperative level considerably higher compared to healthy subjects
Matowicka-Karna et al. 2013 [23]In preoperative gastric cancer associated with the disease progression
Gong et al. 2016 [24]In preoperative pancreatic cancer patients compared to those having benign lesions of the organ and healthy subjects
Yin et al. 2018 [25]Associated with worse survival outcome in patients with pancreatic cancer with synchronous liver metastases
Carlioglu et al. 2014 [26]Observed in papillary thyroid cancer patients, correlated with tumor growth