Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition

Figure 7

The diversity analysis of the intestinal flora of mice. (a) A Venn diagram showing the number of the common and unique bacterial OTUs between the control and aplysin intervention groups. (b) Species accumulation curves and (c) goods_coverage assessing sequencing depth. (d) The Chao1 showing species richness of the intestinal flora. indicates that there was no obvious difference between groups. (e) The Shannon index showing species evenness. indicates that there was no obvious difference between groups. (f) Principal coordinate analysis (PCoA) of intestinal flora among all samples. Cluster of samples implies their species compositions were similar or identical. indicated that the difference between the two groups for the corresponding principal coordinate was obvious. (g) ANOSIM (analysis of similarity). and indicated an obvious difference between these two groups. (h) The heat map based on weighted UniFrac distances of the 10 samples. Proximity of samples indicated similar species compositions.

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