CD4⁺ T Cell Profile and Activation Response in Sickle Cell Disease Patients with Osteonecrosis

Table 2

Demographic and hematology profiles for the bone marrow aspirate, from the SCD and non-SCD groups.

	Non-SCD BM ()	SCD BM ()	value
Age (y)	36 (16-59)	25.7 (9-57)
Male (%)	61.1	50
WBC (×10^3/mm)	7.8 (5.0-24.5)	12.8 (6.2-31.9)	0.081
Lym (%)	34.5 (21.9-48.4)	36.9 (5.2-55.4)	0.450
RBC (×10^6/mm^3)	4.0 (2.1-6.3)	3.1 (1.7-5.2)	0.005
Hgb (g/dL)	12.8 (7.1-17.8)	10.3 (6.7-13.5)	0.026
Hct (%)	36.3 (19.9-57.2)	31.7 (18.0-45.0)	0.058
MCV (fL)	88.9 (78.2-95.1)	103.9 (71.0-135.5)	0.001
MCH (pg)	32.2 (23.3-37.9)	35.6 (25.7-46.1)	0.217
RDW (%)	12.5 (10.2-16.3)	14.8 (10.9-19.4)	0.001
Plat (10^3/μL)	8.0 (6.5-10.2)	8.7 (7.8-9.8)	0.037
CD34^+CD45^low (%)	0.6 (1.3-0.2)	0.5 (1.2-0.2)	0.401

^aResults are presented as median (min–max), except where noted otherwise. WBC: white blood cell; Lym: lymphocytes; RBC: red blood cells; Hgb: hemoglobin; Hct: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; RDW: red cell distribution width; and Plat: platelets. Significance values are presented as ; , , , and .