Elevated Circulating Fetuin-B Levels Are Associated with Insulin Resistance and Reduced by GLP-1RA in Newly Diagnosed PCOS Women

Table 2

The results of linear regression analysis of variables associated with circulating Fetuin-B levels in the study population.

Variable	Fetuin-B		Age-and WHR-adjusted		Multivariate
Age (year)	0.03	NS
BMI (kg/m^2)	0.16	<0.01
WHR	0.16	<0.01	0.06	NS	0.21	<0.05
FAT (%)	0.146	<01	0.07	NS
SBP (mmHg)	0.14	<0.01	0.10	NS
DBP (mmHg)	0.07	NS	0.03	NS
TC (mmol/L)	0.07	NS	-0.03	NS
TG (mmol/L)	0.17	<0.01	0.09	NS
HDL-C (mmol/L)	-0.08	NS	-0.03	NS
LDL-C (mmol/L)	0.12	<0.05	0.06	NS
FFAs (μmol/L)	0.08	NS	-0.09	NS
FBG (mmol/L)	0.18	<0.01	0.20	<0.01
2 h-BG (mmol/L)	0.16	<0.01	0.07	NS
FIns (mU/L)	0.21	<0.01	0.22	<0.01
2 h-Ins (mU/L)	0.16	<0.01	0.06	NS
HOMA-IR	0.21	<0.01	0.25	<0.01
AUCi (mU × h/L)	0.17	<0.01	0.05	NS
AUCg (mmol × h/L)	0.20	<0.01	0.26	<0.01
value (mg/kg/min)	-0.24	<0.01	-0.18	<0.01	-0.400	<0.01
DHEA-S (μg/dL)	-0.03	NS	-0.10	NS
LH (IU/L)	0.09	NS	0.04	NS
FSH (IU/L)	-0.16	<0.01	-0.11	<0.05
Estradiol (pg/mL)	-0.04	NS	-0.03	NS
Prolactin (μg/L)	-0.107	<0.05	-0.05	NS
Prog (nmol/L)	-0.068	NS	0.05	NS
SHBG (nmol/L)	-0.057	NS	0.10	NS
TEST (nmol/L)	-0.003	NS	-0.08	NS
FAI	0.026	NS	-0.03	NS
TNFα (ng/L)	0.212	<0.01	0.04	NS

In multiple linear stepwise regression analysis, values included for analysis were age, BMI, WHR, SBP, DBP, HOMA-IR, FFA, TG, TC, HDL-C, LDL-C, FAT%, DHEA-S, LH, FSH, Prog, and FAI.