Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury

Table 1

Clinical and laboratory variables of 23 cirrhotic patients with AKI.

Characteristics ()	Mean/median/ (%)
Age	55.7
Gender (male/female)	16 (70%)/7 (30%)
Mean blood pressure (mmHg)	64 (±5.8)
Body weight (kg)	72 (±7.7)
Child-Pugh score	10.8 (±1.9)
Child-Pugh class (A/B/C)	0/9 (39%)/14 (71%)
MELD	22.17 (±7.7)
MELD-Na	24.6 (±7.6)
Use of medications
Diuretics	20 (87%)
Nephrotoxic agents	1 (4%)
AKI stages
1	15 (65%)
2	7 (30%)
3	1 (4%)
AKI causes
Infection	13 (56%)
Hypovolemia	9 (39%)
Hepatorenal syndrome	0
Renal disease	1 (4%)
HMGB1 (pg/mL)	1697.2 (0.1-6851.8)
IL-6 (pg/mL)	47.6 (0.1-1107.3)
Creatinine (mg/dL)	1.99 (±0.7)
Total bilirubin (mg/dL)	4.6 (0.4-15.3)
Albumin (g/dL)	2.5 (±0.4)
INR	1.6 (1.0-5.0)
Sodium (mEq/L)	133.6 (±4.8)
C-reactive protein (mg/L)	34 (9-287)

AKI: acute kidney injury.