Mediators of Inflammation / 2020 / Article / Tab 1

Research Article

Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury

Table 1

Clinical and laboratory variables of 23 cirrhotic patients with AKI.

Characteristics ()Mean/median/ (%)

Age55.7
Gender (male/female)16 (70%)/7 (30%)
Mean blood pressure (mmHg)64 (±5.8)
Body weight (kg)72 (±7.7)
Child-Pugh score10.8 (±1.9)
Child-Pugh class (A/B/C)0/9 (39%)/14 (71%)
MELD22.17 (±7.7)
MELD-Na24.6 (±7.6)
Use of medications
 Diuretics20 (87%)
 Nephrotoxic agents1 (4%)
AKI stages
 115 (65%)
 27 (30%)
 31 (4%)
AKI causes
 Infection13 (56%)
 Hypovolemia9 (39%)
 Hepatorenal syndrome0
 Renal disease1 (4%)
HMGB1 (pg/mL)1697.2 (0.1-6851.8)
IL-6 (pg/mL)47.6 (0.1-1107.3)
Creatinine (mg/dL)1.99 (±0.7)
Total bilirubin (mg/dL)4.6 (0.4-15.3)
Albumin (g/dL)2.5 (±0.4)
INR1.6 (1.0-5.0)
Sodium (mEq/L)133.6 (±4.8)
C-reactive protein (mg/L)34 (9-287)

AKI: acute kidney injury.

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