Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells

Figure 5

Effect of SDG on the IκB/NF-κB pathway in LPS-induced HUVECs. (a) Representative immunoblots of p-IκB-α, IκB-α, NF-κB p65, and p-NF-κB p65 proteins in different groups. (b–d) Semiquantitative analysis of the relative levels of p-IκB-α, IκB-α, and p-NF-κB p65/p65 by a densitometric analysis. Error bars represent . , , and represent , , and , respectively. All experiments were performed in triplicate. LPS: lipopolysaccharide; SDG: secoisolariciresinol diglucoside.

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