Research Article

Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway

Table 1

Neurological deficit scores (NDS) for rats.

General behavior
 ConsciousnessNormal (10), stuporous (5), comatose (0)
 ArousalEyes open spontaneously (3), eyes open to pain (1), no eye opening (0)
 RespirationNormal (6), abnormal (0), absent (0)
Brain-stem function
 OlfactionPresent (3), absent (0)
 VisionPresent (3), absent (0)
 Pupillary reflexPresent (3), absent (0)
 Corneal reflexPresent (3), absent (0)
 Startle reflexPresent (3), absent (0)
 Whisker stimulationPresent (3), absent (0)
 SwallowingPresent (3), absent (0)
Motor assessment
 Strength (left and right side tested and scored separately)Normal (3), stiff/weak (1), no movement/paralyzed (0)
Sensory assessment
 Pain (left and right side tested and scored separately)Brisk withdrawal with pain (3), weak or abnormal response (1), no withdrawal (0)
Motor behavior
 Gait coordinationNormal (3), abnormal (1), absent (0)
 Balance on beamNormal (3), abnormal (1), absent (0)
Behavior
 Righting reflexNormal (3), abnormal (1), absent (0)
 Negative geotaxisNormal (3), abnormal (1), absent (0)
 Visual placingNormal (3), abnormal (1), absent (0)
 Turning alleyNormal (3), abnormal (1), absent (0)
Seizures
 Convulsive or nonconvulsiveNo seizure (10), focal seizure (5), general seizure (0)