Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study
Table 1
General characteristics of participants according to tertiles of high-sensitivity CRPa.
Tertiles of high-sensitivity CRP (mg/L)
trendb
Tertile 1 ()
Tertile 2 ()
Tertile 3 ()
High-sensitivity CRP (mg/L)
0.42 (0.41, 0.43)c
0.96 (0.95, 0.97)
3.13 (3.05, 3.22)
Male, (%)
757 (42.06%)
793 (43.81%)
856 (47.32%)
<0.01
Age (years)
56.92 (56.51, 57.34)
58.57 (58.16, 58.98)
59.30 (58.88, 59.71)
<0.0001
BMI (kg/m2)
22.62 (22.44, 22.79)
23.76 (23.59, 23.94)
24.43 (24.25, 24.60)
<0.0001
Education level, (%)
No formal education
395 (21.94%)
421 (23.26%)
395 (21.84%)
0.69
Elementary or below
661 (36.72%)
668 (36.91%)
682 (37.70%)
0.52
Middle school or above
744 (41.33%)
721 (39.83%)
732 (40.46%)
0.77
Smoking status, (%)
Nonsmoker
1187 (65.94%)
1120 (61.88%)
1083 (59.87%)
<0.001
Exsmoker
112 (6.22%)
139 (7.68%)
188 (10.39%)
<0.0001
Current smoker
501 (27.83%)
551 (30.44%)
538 (29.74%)
0.40
Drinking status, (%)
≥1 time/month
460 (25.56%)
423 (23.37%)
426 (23.55%)
0.28
<1 time/month
151 (8.39%)
155 (8.56%)
132 (7.30%)
0.16
Nondrinker
1189 (66.06%)
1232 (68.07%)
1251 (69.15%)
0.07
Fasting plasma glucose, (%)
<110 mg/dL
1399 (77.72%)
1298 (71.71%)
1227 (67.83%)
<0.0001
110-126 mg/dL
263 (14.61%)
290 (16.02%)
316 (17.47%)
0.02
≥126 mg/dL
138 (7.67%)
222 (12.27%)
266 (14.70%)
<0.0001
Income ≥2433.07 yuan/year, (%)
314 (17.44%)
261 (14.42%)
261 (14.43%)
0.05
Married, (%)
1621 (90.06%)
1612 (89.06%)
1592 (88.00%)
0.06
Urban, (%)
534 (29.67%)
613 (33.87%)
670 (37.04%)
<0.0001
Hypertension
398 (22.11%)
507 (28.01%)
615 (34.00%)
<0.0001
Total cholesterol (mg/dL)
190.15 (188.42, 191.87)
194.82 (193.10, 196.54)
196.31 (194.59, 198.03)
<0.0001
Triglycerides (mg/dL)
112.22 (107.62, 116.83)
133.98 (129.39, 138.57)
140.90 (136.31, 145.49)
<0.0001
HDL cholesterol (mg/dL)
55.14 (54.45, 55.83)
50.64 (49.95, 51.33)
48.66 (47.97, 49.35)
<0.0001
eGFR (mL/min per 1.73 m2)
81.71 (81.27, 82.14)
80.04 (79.61, 80.47)
79.68 (79.24, 80.11)
<0.0001
Baseline uric acid (mg/dL)
3.99 (3.94, 4.04)
4.25 (4.20, 4.29)
4.42 (4.37, 4.47)
<0.0001
aCRP: C-reactive protein; BMI: body mass index; HDL: high-density lipoprotein; eGFR: estimate glomerular filtration rate. bAnalysis of variance or logistic regression analysis. cLeast square mean (95% confidence interval) (all such values).
