Mediators of Inflammation / 2020 / Article / Tab 3

Research Article

The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection

Table 3

Univariable and multivariable analysis for overall survival.

VariablesUnivariable analysisMultivariable analysis
HR95% CIHR95% CI

Age (≤60/>60, years)1.1620.693-1.9460.569
Gender (male/female)1.3000.795-2.1260.295
KPS (>80/≤80)0.8410.492-1.4390.527
Smoking status (yes/no)1.8901.028-3.4760.040
Localization (rectum/colon)0.9470.575-1.5600.831
Surgical approach (laparoscopy/open)0.9850.601-1.6150.952
Adjuvant therapy (no/yes)0.6520.398-1.0690.090
CEA (≤5/>5, ng/ml)0.6920.417-1.1470.153
Pathological stage (I–II/III–IV)0.4510.270-0.7550.0020.4420.236-0.8270.011
Differentiated degree (high-middle/minor)0.4760.262-0.8620.014
Lymphatic invasion (yes/no)1.9341.159-3.2270.012
Vascular invasion (yes/no)3.5081.771-5.279<0.0012.1821.243-3.8290.007
ΔSII (>127.7/≤127.7)4.2812.553-7.719<0.0014.3012.517-7.350<0.001

KPS: ∆SII: the change in the systemic immune-inflammation index; KPS: Karnofsky Performance Status; CEA: carcinoembryonic antigen.

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