Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling
Cardiac USP2 is significantly decreased in response to pressure overload. (a–c) Hierarchical clustering and heat map analysis of TAC-related differentially expressed genes in ubiquitin-specific proteases family; (d) Venn diagrams of DGGs; (e) representative Western blot analyses of USP2 and USP18 in the heart tissues. Quantification of the relative protein levels. (f) Representative images of IHC staining of USP2 in the heart sections. , /group.