Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury

Figure 3

Increased level of CCL2 in the brain and serum of acute TBI mice. CCL2 level was quantified by ELISA in the brain tissue lysate and serum of 24 and 72 h acute TBI mice and sham control mice without TBI (). Results show significantly increased level of CCL2 in the (a) brains and (b) sera of both 24 h and 72 h acute TBI as compared with sham control mice (, sham control vs. TBI).

(a)

(b)