The Expression Pattern and Regulatory Mechanism of the G0/G1 Switch Gene 2 (G0S2) in the Pathogenesis and Treatment of AChR Myasthenia Gravis (MG)
G0S2 methylation level in control and MG patients. (a) The positions of two different CpG islands in G0S2 promoter region. Box represents the different CpG islands. Number represents the positions of nucleobase. (b) G0S2 methylation density in the control group; blank circle means result which was not methylation; the black circle means methylation result. (c) G0S2 methylation density in the MG patients. Blank circle means result which was not methylated; the black circle means methylation result. (d) Normalized ratio of G0S2 methylation. MG means the myasthenia gravis patients; ctrl means healthy volunteers. The -coordinate represents the rate of methylation result.
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