Research Article
Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old
Table 2
Significant risk factors for new-onset CV event and CVD mortality.
| | Risk factors | Univariable logistic regression | Multivariable logistic regression | | HR (95% CI) | value | HR (95% CI) | value |
| | New-onset CV event | | | | | | Sex (female vs. male) | 0.58 (0.43-0.79) | 0.001 | 0.56 (0.40-0.77) | <0.001 | | Hypertension (yes vs. no) | 2.63 (1.83-3.79) | <0.001 | 1.72 (1.16-2.56) | 0.008 | | Age (per 1 year greater) | 1.04 (1.03-1.05) | <0.001 | 1.04 (1.03-1.05) | <0.001 | | FBG (mmol/L) | 1.13 (1.07-1.20) | <0.001 | 1.09 (1.03-1.16) | 0.005 | | CCB (yes vs. no) | 1.61 (1.12-2.31) | 0.010 | 1.58 (1.04-2.42) | 0.034 | | Diastolic BP (per 1 mmHg greater) | 0.99 (0.98-1.00) | 0.006 | | | | Creatinine (μmol/L) | 0.999 (0.998-1.001) | <0.001 | | | | Phosphorus (mmol/L) | 0.70 (0.53-0.92) | 0.012 | | | | RRF (mL/min) | 0.99 (0.98-1.00) | 0.032 | | | | Center (C4 vs. C1) | 0.50 (0.31-0.81) | 0.005 | | | | Diabetes (yes vs. no) | 2.35 (1.72-3.20) | <0.001 | | | | CVD disease (yes vs. no) | 2.12 (1.50-3.00) | <0.001 | | | | Diuretic (yes vs. no) | 1.79 (1.09-2.94) | 0.022 | | | | Insulin (yes vs. no) | 2.27 (1.61-3.20) | <0.001 | | | | CVD mortality | | | | | | Center (C4 vs. C1) | 0.40 (0.21-0.75) | 0.004 | 0.49 (0.25-0.94) | 0.032 | | Hypertension (yes vs. no) | 3.10 (1.98-4.85) | <0.001 | 1.72 (1.06-2.79) | 0.027 | | Diabetes (yes vs. no) | 3.32 (2.36-4.69) | <0.001 | 2.10 (1.42-3.10) | <0.001 | | CVD disease (yes vs. no) | 2.59 (1.77-3.79) | <0.001 | 1.66 (1.07-2.56) | 0.024 | | Age (per 1 year greater) | 1.04 (1.03-1.06) | <0.001 | 1.03 (1.02-1.05) | <0.001 | | Diastolic BP (per 1 mmHg greater) | 0.99 (0.98-1.00) | 0.020 | | | | Albumin (g/L) | 0.97 (0.94-1.00) | 0.039 | | | | Creatinine (μmol/L) | 0.999 (0.998-0.999) | <0.001 | | | | Urea nitrogen (mmol/L) | 0.97 (0.95-0.99) | 0.001 | | | | FBG (mmol/L) | 1.08 (1.02-1.15) | 0.010 | | | | Chlorine (mmol/L) | 1.04 (1.01-1.07) | 0.014 | | | | Phosphorus (mmol/L) | 0.61 (0.43-0.85) | 0.003 | | | | RRF (mL/min) | 0.98 (0.96-1.00) | 0.014 | | | | Diuretic (yes vs. no) | 1.91 (1.10-3.31) | 0.022 | | | | Insulin (yes vs. no) | 2.41 (1.64-3.55) | <0.001 | | |
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Abbreviations: CVD: Cardiovascular disease; C1: center 1; C4: center 4; BP: blood pressure; CCB: calcium channel blocker; RRF: residual renal function; FBG: fasting blood glucose; HR: hazard ratio; CI: confidence interval.
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