Research Article

Relationship of Serum Levels of IL-17, IL-18, TNF-α, and Lung Function Parameters in Patients with COPD, Asthma-COPD Overlap, and Bronchial Asthma

Table 5

Correlation between the serum concentration TNF-α and the lung function parameters in patients with COPD, asthma-COPD overlap, and bronchial asthma.

Spirometric indicatorsCOPDACOBA

FVC (l)-0.320.03-0.360.051-0.250.35
FVC (%)-0.520.001-0.1260.51-0.190.53
FEV1 (l)-0.3180.040.0060.97-0.470.03
FEV1 (%)-0.3640.0180.1920.18-0.430.04
FEV1/FVC (%)-0.340.02-0.4050.02-0.210.36
FEF25 (l)-0.2790.0740.2660.15-0.270.33
FEF25 (%)-0.3130.0440.1950.18-0.10.73
FEF50 (l)-0.2740.0790.2230.23-0.260.34
FEF50 (%)-0.3280.034-0.3610.050.10.74
FEF75 (l)-0.240.120.0870.640.250.35
FEF75 (%)-0.2670.0870.2210.24-0.120.7
IC (%)-0.1910.2260.2120.26-0.240.35

: correlation coefficient; COPD: chronic obstructive pulmonary disease; ACO: asthma-COPD overlap; BA: bronchial asthma.