Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway

Figure 5

AE has an important repressor effect on the PA-induced TLR4 pathway signaling. The extracted total proteins were processed to western blot analysis with GAPDH as the loading control. The column figures demonstrated the normalized optical density of (a) Toll-like receptor 4 (TLR4), (b) inhibitor of NF-κB (IκB), (c) nuclear factor-kappa B P65 (NF-κB P65), and (d) p-nuclear factor-kappa B P65 (p-NF-κB P-P65) proteins (; and compared to the control group; ^## and ^### compared to the PA group).

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